June 17, 2014 Since the approval of Dry Powder Inhalers containing Fluticasone Propionate and Salmeterol Xinafoate in 1999, combination inhaled therapies have dominated the COPD market. However, due to the lack of specific guidance of the Office of Generic Drugs as to the abbreviated new drug application submission, there was…
Download our presentation from 2018 RDD Conference on Analysis of a Dry Powder Inhaler Active Pharmaceutical Ingredient Using Scanning Electron Microscopy.
December 11, 2014 The impact of foreign particulate and agglomerates on dissolution profile and permeability of the inhalable drug particles within the sites of action (i.e. patient’s lungs) is critical. In this study, Raman Chemical Imaging (RCI) and Raman/ Laser-induced breakdown spectroscopy (LIBS) were used to investigate the Active Pharmaceutical…
Authors & ContributorsRebekah ByrneDavid ExlineEmily Landsperger
June 04, 2013 Authored by Oksana Olkhovyk, Ph.D., at Gateway Analytical , this poster presents new qualitative and semi-qualitative methods for the examination of size and polymorph drug particle identification in finished products. Specifically, its benefits for BA/BE testing is described using the model of fluticasone-containing nasal spray suspension formulation.…
Authors & Contributors David Exline Emily Landsperger Cara Plese November 19, 2014 Gunshot residue analysis is a common request in forensic laboratories with cases that question whether or not anindividual fired a firearm. When a firearm is fired, several types of residues are expelled from the openings on the firearm. Primer residues, specifically,…
In this study, Raman Chemical Imaging (RCI) was used to investigate the active pharmaceutical ingredients (API) particle size distribution (PSD) and degree of drug particle aggregation in a commercial…